Prof. Thomas Roeder

Molecular Physiology

The major goal of our research is to understand the molecular mechanisms that underlie the development of lifestyle associated diseases, such as asthma, cancer, metabolic disorders or inflammatory bowel diseases. In order to achieve this aim, we rely on the concept of Evolutionary Medicine using the fruit fly Drosophila melanogaster as a model. Utilizing the unique tools available for genetic manipulation of the fly, suitable models, including humanized ones, are generated and analysed in depth to unravel the molecular events associated with these complex diseases.

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Prof. Thomas Roeder

Kiel University

Tel.: +49 (0) 431-880-4181

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Selected Publications

  • Fink C, et al. (2016) Intestinal FoxO signaling is required to survive oral infection in Drosophila. Mucosal Immunol 9(4):927–936.
  • Schneider SA, et al. (2016) Social stress increases the susceptibility to infection in the ant Harpegnathos saltator. Sci Rep 6. doi:10.1038/srep25800.
  • Kallsen K, et al. (2015) ORMDL deregulation increases stress responses and modulates repair pathways in Drosophila airways. Journal of Allergy and Clinical Immunology 136(4):1105–1108.
  • Hoffmann J, Romey R, Fink C, Yong L, Roeder T (2013) Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila. Aging (Albany NY) 5(4):315–327.
  • Roeder T (2005) TYRAMINE AND OCTOPAMINE: Ruling Behavior and Metabolism. Annual Review of Entomology 50(1):447–477.